Baker Mayfield, Browns: Suffered a torn labrum in his shoulder and will miss Week 7 and possibly beyond. Case Keenum will start in his place.
Kareem Hunt & Nick Chubb, Browns: Both left with calf injuries, and Hunt will miss up to 6 weeks while Chubb is likely to miss at least one. D’Ernest Johnson suddenly becomes the bellcow in Cleveland.
Latavius Murray, Ravens: Suffered and ankle injury and remains questionable. Le'Veon Bell and Devonta Freeman would like split time in his absence.
Antonio Gibson, WFT: Left with a shin injury and is questionable for Week 7. Jaret Patterson and JD McKissic would pick up the slack if Gibson misses time.
Kadarius Toney, Giants: Left with an ankle injury and is expected to miss 1-2 games. Sterling Shepard will get a bump in his absence.
Julio Jones, Titans: Suffered a hamstring injury and is questionable for Week 7. Nick Westbrook-Ikhine would start in his place.
Antonio Brown, Bucs: Has an ankle injury and is questionable for Week 7. All other Buc’s wideout get a bump if Brown misses time.
Odell Beckham, Browns: Left with a shoulder injury and remains questionable. Donovan Peoples-Jones would be the biggest beneficiary if Beckham is out.
Ricky Seals-Jones, WFT: Suffered a quad injury and is questionable for Week 7. Jon Bates is next on deck.
Dawson Knox, Bills: Suffered a broken hand and had surgery. Expected to miss the next few weeks. Tommy Sweeney will be the primary TE while Knox is out.